Active Protocols These protocols were designed and developed by the Radiation Therapy Oncology Group (RTOG) of the American College of Radiology (ACR). They are intended to be used only in conjunction with institution-specific IRB approval for study entry. No other use or reproduction is authorized by RTOG nor does RTOG assume any responsibility for unauthorized use of this protocol. Active Links Brain Tumor Protocols Endorsed Studies Breast Cancer Protocols Gynecologic Cancer Protocols Symptom Management/Cancer Prevention Protocols Head & Neck Cancer Protocols Gastrointestinal Cancer Protocols Lung Cancer Protocols Genitourinary Cancer Protocols Sarcoma Protocols Brain Tumor Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCAST 0627 Phase II GBM (Temporarily closed ) Consent & 0627 Forms 0627 Changes 0627 Broadcast 0625/ACRIN 6677 Phase II GBM (Temporarily closed) Consent & 0625 Forms& 0625/6677 Overview& 0625/6677 ITW & 0625/6677 CRS & 0625/6677 PSA 0625 Changes 0625 Broadcast 0614 Phase III Memantine/Placebo/WBRT (Activation: 03/28/08) Consent & 0614 Forms & Shipment Form & IND Exemption 0614 Changes 0614 Broadcast 0611 GBM VEGF/MMP (Closed to Accrual) Consent & 0611 Forms 0611 Changes 0611 Broadcast 0525 Phase III GBM (Closed to accrual; 2nd step registration OPEN) (No Investigator Brochure) Consent & 0525 Forms & Shipment form (save as word.doc)& EORTC Information [PDF] & Patients Brochure [PDF]& NCCTG Information [PDF]& IND Exemption & MD Anderson Cancer Ctr & Training Procedure Letter & Neurocognitive Certification Worksheet 0525 Changes 0525 Broadcast 0513 Phase I/II GBM Arm 4 open Consent & 0513 Forms 0513 Changes 0513 Broadcast 0424 Phase II Brain (Activation: 1/26/05) Consent & 0424 Forms & Shipment Form 0424 Changes 0424 Broadcast 0420 Phase II (Closed to Accruals) Consent & 0420 Forms 0420 Changes 0420 Broadcast 0320 Phase III (Activation: 10/06/04) Consent & 0320 Forms & Shipment Form (save as word.doc)& Presentation & Summary 0320 Changes 0320 Broadcast 0227 Phase I/II Appendix III & Consent & 0227 Forms & Shipment form (save as word.doc) 0227 Changes 0227 Broadcast 0211 GBM (Closed to Accruals) Appendix III & Consent & 0211 Forms 0211 Changes 0211 Broadcast BR-0131 Phase II (Closed to Accruals) Appendix IV & Consent & BR-0131 Forms BR-0131 Changes BR-0131 Broadcast BR-0119 Metastasis (Closed to Accruals) Appendix III & Consent & BR-0119 Forms BR-0119 Changes BR-0119 Broadcast BR-0118 Metastases (Closed to Accruals) Appendix III & Consent & BR-0118 Forms BR-0118 Changes BR-0118 Broadcast BR-0023 Glioma (Closed to Accruals) Appendix III & Consent & BR-0023 Forms BR-0023 Changes   BR-0021 GBM Tamoxifen (Closed to Accruals) Appendix III& Consent BR-0021 Changes   BR-0013 GBM Bleomycin (Closed to Accruals) Appendix III & Consent & BR-0013 Forms BR-0013 Changes BR-0013 Broadcast 9813 Astrocytoma (Closed to Accruals) Appendix IV & Consent & 9813 Forms & Investigator Brochures 9813 Changes 9813 Broadcast 9806 GBM/Thalidomide (Closed to Accruals) Appendix III & Consent 9806 Changes 9806 Broadcast 9803 3D GBM (Closed to Accruals) Appendix IV & Consent & 9803 Forms 9803 Changes 9803 Broadcast 9802 Low Grade Glioma (Closed to Accruals) Appendix IV & 9802 Forms 9802 Changes 9802 Broadcast 9710 GBM Beta Inf. (Closed to Accruals) Appendix IV 9710 Changes   9402 Oligodendroglioma (Closed to Accruals) Appendix IV 9402 Changes 9402 Broadcast 9110 Phase III     9110 Broadcast Breast Cancer Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCAST NSABP B-39/RTOG 0413 (Activation: 3/21/05) Consent in English & Consent in French & Consent in Spanish & Patient Entry Procedure [PDF] & Credentialing info [PDF] & Common Active Sites [XLS] & Fact Sheet [PDF] & Cosmesis digital photo resubmission memo [PDF] & Memo 12-12-06 [PDF] & Memo 12-22-06 [PDF] & Time ranges for QOL/cosmesis [PDF] 0413 changes [PDF] 0413 Broadcast 0319 Breast Phase I/II (Closed to Accruals) Appendix IV & Consent & 0319 Forms 0319 Changes 0319 Broadcast 9804 Breast DCIS (Closed to Accruals) App. IV | Diag. 1 | Diag. 2 & Consent & 9804 Forms & Investigator Summary 9804 Changes 9804 Broadcast 9702 Breast Tamoxifen (Closed to Accruals)   9702 Changes   9517 Breast Brachytherapy (Closed to Accruals)   9517 Changes 9517 Broadcast Symptom Management/Cancer Prevention Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCAST 0518 Phase III Prevent Osteo (Activation: 03/28/06) Consent & 0518 Forms & Shipment Form 0518 Changes 0518 Broadcast 0517 Palliation Bone Mets (Activation: 07/11/06) Consent & 0517 Forms & Dental Checklist & Shipment Form & Patient Brochure & Slide Set & Letter to Investigators [DOC] 0517 Changes 0517 Broadcast 0435 H&N/Palifermin (Closed to Accrual) Consent & 0435 Forms & AE Grading Tool 0435 Changes 0435 Broadcast 0433 Phase III (Activation: 3/31/05)     0433 Broadcast 0315 Phase III (Closed to Accruals) Consent & 0315 Timeline & 0315 Forms 0315 Changes 0315 Broadcast 0215 Prostate Cancer (Closed to Accruals) Consent & 0215 Forms 0215 Changes 0215 Broadcast 0127 Phase III NSCLC (Activation: 10/5/01)   0127 Changes 0127 Broadcast 0123 Phase II Lung (Closed to Accruals) Consent & 0123 Forms 0123 Changes 0123 Broadcast 0122 Cancer Cachexia (Closed to Accruals) Consent & 0122 Forms 0122 Changes 0122 Broadcast 9913 H & N/Biafine (Closed to Accruals) 9913 Forms   9913 Broadcast 9901 H & N GM-CSF (Closed to Accruals) Appendix IV & 9901 Forms 9901 Changes   9714 Bone Metastases (Closed to Accruals) Appendix IV & 9714 Forms 9714 Changes   9604 Late Effects (LENT) (Closed to Accruals)   9604 Changes   Gastrointestinal Cancer Protocols 0822 Phase II Rectal (Activation: 4/29/08) Consent & 0822 Forms & IND Exemption 0822 Broadcast 0529 Ph II Anal Canal (Closed to Accruals) Consent & 0529 Forms 0529 Changes 0529 Broadcast 0438 Phase I Liver (Temporarily Closed) Consent & 0438 Forms 0438 Changes 0438 Broadcast 0436 Phase III Esophagus (Activation: 6/30/08) Consent & 0436 Forms & Study Agent Shipment Form & Investigator Brochures 0436 Changes 0436 Broadcast 0411 Phase II Pancreas (Closed to Accruals) Consent & 0411 Forms 0411 Changes 0411 Broadcast 0247 Phase II Rectal (Closed to accrual) Consent & 0247 Forms 0247 Changes 0247 Broadcast 0246 Phase II (Closed to Accruals) Consent & 0246 Forms 0246 Changes 0246 Broadcast G-0114 Gastric (Closed to Accruals) Appendix IV & Consent & 0114 Forms G-0114 Changes G-0114 Broadcast 0113 Esophagus (Closed to Accruals) Appendix IV & Consent & 0113 Forms 0113 Changes 0113 Broadcast PA-0020 Pancreas (Closed to Accruals) Appendix IV & Consent & 0020 Forms PA-0020 Changes PA-0020 Broadcast R-0012 Rectum (Closed to Accruals) Appendix IV & Consent & R-0012 Forms R-0012 Changes R-0012 Broadcast 9904 Stomach (Closed to Accruals) Appendix IV & Consent & 9904 Forms 9904 Changes 9904 Broadcast 9811 Anal Canal (Closed to Accruals) Appendix IV & Consent & 9811 Forms 9811 Changes 9811 Broadcast 9716 CALGB Esophagus (Closed to Accruals)   9716 Changes   9704 Pancreas (Closed to Accruals) 9704 Diagrams & 9704 Forms 9704 Changes 9704 Broadcast 9415 Colectomy (LP) (HP) (Closed to Accruals)   9415 Changes   9405 Esophagus (Closed to Accruals) Appendix IV 9405 Changes   9403 Rectum (Closed to Accruals)   9403 Changes 9403 Broadcast 9018 Gastric (Closed to Accruals)   9018 Changes 9018 Broadcast Genitourinary Cancer Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCASTS 0622 Phase II Prostate Samarium (Activation: 4/03/08) Consent & 0622 Forms & Shipment Form & IND Exemption 0622 Changes 0622 Broadcast 0621 Phase II Prostate (Activation: 4/08/08) Consent & 0621 Forms & Shipment Form & IND Exemption 0621 Changes 0621 Broadcast 0612 Prostate DNA Microarray (Activation: 6/20/06) Consent 0612 Changes 0612 Broadcast 0534 Phase III Prostate. (Activation: 02/13/2008) Consent & 0534 Forms & IND Exemption 0534 Changes 0534 Broadcast 0526 Phase II Prostate Brachy (Activation: 5/11/07) Consent & 0526 Forms 0526 Changes 0526 Broadcast 0521 Phase III Prostate (Activation: 12/08/05) 1.5 Case Credits Consent & 0521 Forms Shipment Form & Tissue Consent 0521 Changes 0521 Broadcast 0524 Phase I/II Bladder (Activation: 7/26/05) Consent & 0524 Forms 0524 Changes 0524 Broadcast 0415 Phase III Prostate (Activation: 4/18/06) Consent & 0415 Forms & Tissue Consent 0415 Changes 0415 Broadcast 0321 Phase II Prostate (Closed to Accruals) Consent & 0321 Forms 0321 Changes 0321 Broadcast 0233 Bladder Cancer (Closed to Accrual) Consent & 0233 Forms 0233 Changes 0233 Broadcast 0232 Phase III Prostate (Activation: 6/11/03) Appendix IV & Consent & 0232 Forms & Patients Brochure 0232 Changes 0232 Broadcast 0126 Prostate (Activation: 3/21/02) Appendix IV & Consent & 0126 Forms & Tissue Consent 0126 Changes 0126 Broadcast P-0019 Prostate Brachy (Closed to Accruals) Appendix IV & Consent & 0019 Forms P-0019 Changes    9910 Prostate (Closed to Accruals) Appendix IV & Consent & 9910 Forms 9910 Changes 9910 Broadcast 9906 Bladder (Closed to Accruals) App. IV | App. VII 9906 Changes   9902 Prostate (Closed to Accruals) Appendix IV & Consent & 9902 Forms 9902 Changes 9902 Broadcast 9805 Prostate Implant (Closed to Accruals) Appendix IV     9706 Bladder (Closed to Accruals 6/1/99) Appendix IV 9706 Changes   9608 pN+ Prostate (Closed to Accruals)   9608 Changes   9601 Prostate +/- Casodex (Closed to Accruals) Appendix IV & Consent & 9601 Forms 9601 Changes 9601 Broadcast 9506 Bladder   9506 Changes 9506 Broadcast 9413 Pros/Adv. (Closed to Accruals) Appendix IV & 9413 Forms 9413 Changes 9413 Broadcast 9408 Prostate/Early (Closed to Accruals) Appendix IV & 9408 Forms 9408 Changes 9408 Broadcast 9406 Prostate (Closed to Accruals) 9406 Forms& Consent 9406 Changes 9406 Broadcast 9019 Prostate (Closed to Accruals)   9019 Changes 9019 Broadcast 8903 Phase III Bladder     8903 Broadcast 8531 Phase III Prostate (Closed to Accruals) 8531 Forms & Consent & Appendix VI 85-31 Changes 8531 Broadcast 9202 Phase III Prostate (Closed to Accruals) 9202 Forms & Appendix IV Gynecologic Cancer Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCASTS 0418 Phase II IMRT (Endometrial arm closed) Consent & 0418 Forms 0418 Changes 0418 Broadcast 0417 Phase II Cervix/Bevacizumab (Activation: 08/11/2006) Consent & 0417 Forms 0417 Changes 0417 Broadcast C-0128 Cervix/Celebrex (Closed to Accruals) Appendix IV & Consent & 0128 Resupply Request Form (save as word doc) & 0128 Forms C-0128 Changes C-0128 Broadcast 0116 Cervix (Closed to Accruals) Consent & 0116 Forms 0116 Changes 0116 Broadcast 9905 Endometrium (Closed to Accruals) Appendix IV & Consent & 9905 Forms 9905 Changes 9905 Broadcast 9708 Endometrium (Closed to Accruals) 9708 Diagrams 9708 Changes   9112 Cervix/Post-Op (Closed to Accruals)     9112 Broadcast Head & Neck Cancer Protocols PDF FORMAT (Requires Acrobat Reader) MISCELLANEOUS (That Are N/A In PDF) SUMMARY OF CHANGES BROADCASTS 0615 Phase II Nasopharyngeal (Activation: 12/13/06) Consent & 0615 Forms & AE Grading Tool 0615 Changes 0615 Broadcast 0522 Advanced H & N (Activation: 11/22/05) Consent & 0522 Forms & AE Grading Tool & Init Shipment Form & Resupply Shipment Form (save as word doc) & Medicare MD Info & Medicare Reimbursement 0522 Changes 0522 Broadcast 0514 H&N Cancer Tissue/Specimen Bank (Activation: 9/26/05) Consent & 0514 Forms 0514 Changes 0514 Broadcast 0435 H&N/Palifermin (Closed to Accrual) Consent & 0435 Forms & AE Grading Tool & Mucositis Training Instructions& Lab Supply Request Form 0435 Changes 0435 Broadcast 0421 Phase III Head & Neck (Closed to Accruals) Consent & 0421 Forms 0421 Changes 0421 Broadcast 0244 Phase II H & N (Closed to accrual) Appendix IV & Consent & 0244 Forms 0244 Changes 0244 Broadcast 0234 Phase II (Closed to Accruals) Consent & Shipment form (save as word.doc) & 0234 Forms 0234 Changes 0234 Broadcast 0225 Nasopharyngeal (Closed to Accruals) Appendix IV & Consent & 0225 Forms 0225 Changes 0225 Broadcast 0129 Advanced H & N (Closed to Accruals) Appendix IV & Consent & 0129 Forms 0129 Changes 0129 Broadcast H-0024 Resected H & N (Closed to Accruals) Appendix IV & Consent & H-0024 Forms H-0024 Changes H-0024 Broadcast 0022 IMRT Oropharynx (Closed to Accruals) Appendix IV & Consent & 0022 Forms 0022 Changes 0022 Broadcast 9914 Adv. H & N (Closed to Accruals)   9914 Changes   9911 Rec. H & N (Closed to Accruals) Consent & 9911 Forms 9911 Changes   9903 H & N Epo (Closed to Accruals) Appendix IV & Consent & 9903 Forms 9903 Changes 9903 Broadcast